Product Name Sacubitril Valsartan Sodium
CAS Number 936623-90-4
Formula C48H53N7O7
Molar Mass 893.97 g/mol
Pub Chem CID 23632005
Drug Bank DB11629
Chem Spider 32765935
Bioavailability 60%
Protein Binding 94%
Metabolism Hepatic
Elimination Halflife 1-2 hours
FAQ
What is Sacubitril Valsartan Sodium (Lcz696)?

Sacubitril Valsartan Sodium, also known as Lcz696, is a combination medication used to treat heart failure. It combines two drugs, sacubitril and valsartan, to help improve the heart's ability to pump blood efficiently.

How does Sacubitril Valsartan Sodium work?

Sacubitril Valsartan Sodium works by inhibiting an enzyme called neprilysin, which normally breaks down substances that promote blood vessel constriction and sodium retention. By inhibiting this enzyme, blood vessels dilate, sodium excretion increases, and the heart can pump blood more effectively.

Is Sacubitril Valsartan Sodium suitable for use in the feed industry?

No, Sacubitril Valsartan Sodium is a medication intended for human use only and should not be used in the feed industry for animals.

What are the potential side effects of Sacubitril Valsartan Sodium?

Some common side effects of Sacubitril Valsartan Sodium include dizziness, low blood pressure, cough, and high levels of potassium in the blood. It is important to speak with your healthcare provider if you experience any side effects while taking this medication.

Can Sacubitril Valsartan Sodium be used in combination with other medications?

Sacubitril Valsartan Sodium should not be used with ACE inhibitors or aliskiren. It is important to talk to your doctor about all medications you are currently taking before starting Sacubitril Valsartan Sodium.

Is it safe to take Sacubitril Valsartan Sodium during pregnancy?

Sacubitril Valsartan Sodium should not be used during pregnancy as it can harm an unborn baby. It is important to use effective birth control while taking this medication and discuss any potential risks with your healthcare provider.

How should Sacubitril Valsartan Sodium be taken?

Sacubitril Valsartan Sodium is typically taken twice daily with or without food. It is important to follow your healthcare provider's instructions on how to take this medication and not to miss any doses.

Can Sacubitril Valsartan Sodium be taken by children?

Sacubitril Valsartan Sodium is not recommended for use in children under 18 years old. It is important to consult with a healthcare provider to determine the appropriate treatment options for pediatric patients with heart failure.

What should I do if I miss a dose of Sacubitril Valsartan Sodium?

If you miss a dose of Sacubitril Valsartan Sodium, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed dose.
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